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Blood Clots After Orthopedic Surgery: Causes, Symptoms & Prevention

By Dr. L. Tomar in Orthopaedics & Joint Replacement

Mar 06 , 2025 | 7 min read

Managing Blood Clots and Deep Vein Thrombosis After Orthopedic Surgery: A Comprehensive Guide

Orthopaedic surgeries, such as joint replacements, fracture repairs, and spinal procedures, are life-changing interventions that restore mobility and improve quality of life. However, like any surgical procedure, they come with potential risks. One of the most serious complications following orthopaedic surgery is the development of blood clots, particularly deep vein thrombosis (DVT).

Deep Vein Thrombosis (DVT) develops when a blood clot forms in a deep vein, typically in the legs. Without treatment, it may cause a life-threatening pulmonary embolism (PE) if the clot travels to the lungs. Understanding how to manage and prevent blood clots after orthopedic surgery is crucial for a safe and successful recovery.

What Causes Blood Clots After Orthopedic Surgery?

Blood clots are a natural response to injury, helping to prevent excessive bleeding. However, certain factors can increase the risk of abnormal clot formation after surgery. These include:

  • Immobility: Patients often experience reduced mobility after surgery, which slows blood circulation and increases the risk of clot formation. When you’re immobile, blood flow in the veins slows down, particularly in the legs. This stagnation of blood can lead to clot formation. Orthopaedic surgeries often require patients to stay in bed or limit movement for extended periods, making immobility a significant risk factor.
  • Surgical Trauma: Orthopedic surgeries, especially those involving the lower extremities, can damage blood vessels, triggering clot formation. The physical trauma from surgery can injure the walls of blood vessels, causing them to narrow or become irregular. This damage can activate the body’s clotting mechanism, leading to the formation of clots at the site of injury.
  • Hypercoagulability: The body’s natural response to surgery includes increased blood clotting to prevent bleeding, but this can sometimes go overboard. Surgery triggers a state of hypercoagulability, where the blood becomes “stickier” and more prone to clotting. While this helps prevent excessive bleeding, it may also raise the risk of unusual blood clot formation in the veins.
  • Age and Health Factors: Older adults, individuals with obesity, or those with a history of blood clots are at higher risk. Age-related changes in blood vessels and circulation, combined with other health conditions like diabetes or heart disease, can increase the likelihood of clot formation. Obesity adds pressure on the veins, further impairing blood flow.
  • Prolonged Surgery Duration: Longer surgeries increase the risk of clot formation due to extended periods of immobility. The longer the surgery, the more time the patient spends immobilised under anaesthesia. This prolonged immobility can significantly increase the risk of blood pooling and clot formation.

Symptoms of Deep Vein Thrombosis (DVT)

Recognising the signs of DVT early is critical for prompt treatment. Common symptoms include:

  • Swelling in the affected leg (usually one side). Swelling occurs because the clot obstructs blood flow, causing fluid to accumulate in the tissues. This swelling is often localised to the leg where the clot has formed.
  • Pain or tenderness often starts in the calf. The pain is caused by inflammation and pressure from the clot. It may feel like a cramp or soreness and is often exacerbated when walking or standing.
  • Redness or warmth over the affected area. The area around the clot may become red and warm due to inflammation and increased blood flow to the site.
  • Visible veins that appear more prominent. The veins may become more visible as blood pools behind the clot, causing them to swell and stand out.

Contact your healthcare provider immediately if you experience any of these symptoms after surgery. In some cases, DVT may not present obvious symptoms, which is why preventive measures are so important.

Preventing Blood Clots After Orthopedic Surgery

Prevention is the best strategy when it comes to managing blood clots. Here are some effective methods to reduce the risk of DVT after orthopaedic surgery:

Medications (Anticoagulants) Blood Thinners

Medications like heparin, warfarin, or newer oral anticoagulants (e.g., rivaroxaban) are commonly prescribed to prevent clot formation. These medications help prevent blood clotting by disrupting the body's natural clotting process. They are often prescribed for a few weeks to months after surgery, depending on the patient’s risk factors. In some cases, low-dose aspirin may be recommended for clot prevention. Aspirin helps prevent platelets from sticking together, reducing the risk of clot formation. It is often used in patients with a lower risk of DVT.

Compression Devices

Intermittent Pneumatic Compression (IPC) devices use controlled air pressure to gently massage the legs, improving circulation and enhancing blood flow. IPC devices are often used in hospitals. They consist of sleeves that wrap around the legs and inflate at regular intervals, mimicking the natural muscle contractions that help blood flow. Compression Stockings: Elastic stockings help prevent blood from pooling in the legs. Compression stockings gently squeeze the legs to improve blood circulation and lower the risk of blood clots. They are commonly advised for patients before and after surgery.

Early Mobilisation

Getting moving as soon as possible after surgery is one of the most effective ways to prevent clots.

Even simple leg exercises or short walks can make a big difference. Movement helps stimulate blood flow, reducing the risk of blood pooling and clot formation. Patients are often encouraged to start moving within 24 hours of surgery, even if it’s just flexing their feet or walking a few steps.

Hydration

Staying well-hydrated helps maintain healthy blood viscosity, reducing the risk of clot formation. Dehydration can make blood thicker, increasing the risk of clotting. Staying well-hydrated helps maintain smooth blood flow.

Lifestyle Modifications

Quit Smoking: Smoking harms blood vessels and raises the likelihood of blood clots, increasing the risk of clot formation. Quitting smoking before and after surgery can reduce this risk.

Healthy Diet: A diet rich in fruits, vegetables, and whole grains supports cardiovascular health. A healthy diet helps maintain optimal blood pressure and cholesterol levels, reducing the risk of clot formation. Foods rich in omega-3 fatty acids, like fish, can also support vascular health.

Treatment Options for Blood Clots and DVT

If a blood clot is detected, prompt treatment is essential to prevent complications. Treatment options include:

Anticoagulant Therapy

Blood thinners are the primary treatment for DVT. They prevent existing clots from growing and reduce the risk of new clots forming. Anticoagulants like heparin, warfarin, or direct oral anticoagulants (DOACs) are used to thin the blood and prevent further clotting. Treatment usually lasts for several months, depending on the severity of the clot.

Thrombolytic Therapy

In severe cases, clot-dissolving medications may be used to break up the clot quickly. Thrombolytics, such as alteplase, are used in life-threatening situations, such as when a clot has travelled to the lungs (pulmonary embolism). These medications are administered in a hospital setting under close supervision.

Inferior Vena Cava (IVC) Filter

For patients who cannot take blood thinners, a small filter may be placed in the vena cava to catch clots before they reach the lungs. An IVC filter is a small device inserted into the vena cava, the large vein that carries blood to the heart. It prevents clots from reaching the lungs, lowering the risk of pulmonary embolism.

Compression Therapy

Compression stockings can help reduce swelling and prevent post-thrombotic syndrome, a long-term complication of DVT. Post-thrombotic syndrome occurs when a clot damages the veins, leading to chronic pain, swelling, and skin changes. Compression stockings help improve blood flow and reduce these symptoms.

Surgical Intervention

In rare cases, surgery may be required to remove a large or life-threatening clot. Surgical procedures, such as thrombectomy, involve removing the clot directly from the vein. This is usually reserved for severe cases where other treatments are ineffective.

Recovery and Long-Term Management

Recovering from DVT requires ongoing care to prevent recurrence and manage complications. Here are some tips for long-term management:

Follow Your Doctor’s Instructions

Take your medications as instructed and ensure you attend all scheduled follow-up appointments. Adhering to your treatment plan is crucial for preventing recurrence and managing complications. Routine check-ups help your doctor track your health and make necessary adjustments to your treatment plan.

Stay Active

Regular physical activity improves circulation and reduces the risk of future clots. Activities such as walking, swimming, or yoga can help maintain healthy blood flow. Avoid prolonged periods of sitting or standing, and take breaks to move around if you have a sedentary job.

Monitor for Symptom

Be vigilant for signs of recurrent DVT or pulmonary embolism, such as chest pain, shortness of breath, or sudden leg swelling. Early detection of symptoms can prevent serious complications. If you notice any signs of a clot, seek medical attention immediately.

Wear Compression Stockings

These can help manage swelling and improve blood flow in the legs. Compression stockings are often recommended for long-term use in patients who have had DVT. They help prevent post-thrombotic syndrome and improve overall leg health.

 

Conclusion

Managing blood clots and deep vein thrombosis after orthopedic surgery is a critical aspect of post-operative care. By understanding the risks, recognising the symptoms, and following preventive measures, patients can significantly reduce their chances of developing DVT and its potentially life-threatening complications.

If you or a loved one is undergoing orthopedic surgery, work closely with your healthcare team to create a personalised prevention and recovery plan. Remember, early intervention and proactive care are key to a safe and successful recovery.